"Drawing on themes that Bram Stoker hints at darkly in his 1897 novel, screenwriter Stewart Harcourt recasts the plot to focus on the Victorians' anxiety about sex and especially syphilis. Some scholars believe that Stoker himself died from syphilis, but the evidence is inconclusive. Nonetheless, the novel could not be more explicit about the invisible infection that seeps into the bloodstream and slowly turns its victims into demented fiends: which is what Dracula does to his prey and also what syphilis often produced in the age before antibiotics."
Something E. Michael Jones writes at length about in Monsters of the Id.
Sophia Myles is in this as Lucy! Too bad I missed most of her parts, since I didn't tune in until the movie was past half-way.
The story has been changed a bit from the original novel--it's not clear to me why they thought this was necessary...
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